Jimmy Carter was the first president to be born in a hospital.
John F. Kennedy was the first president to be born in the 20th century. Andrew Jackson was the first president to be born in a log cabin (there were six more). James Garfield was the last president to be born in a log cabin. Martin Van Buren was the first U.S. president to be born in the United States! (The previous presidents were born before the adoption of the U.S. Constitution.)
(source)
