On The Concert for Bangladesh, Clapton performed the song on a Gibson Byrdland hollow body guitar, and later acknowledged that a solid-body guitar would have been more appropriate.
The version in the Prince’s Trust Rock Concert 1987 reunited Harrison, Starr and Clapton, and features an extended coda with the guitars of Harrison and Clapton interweaving. Mark King played McCartney's bass line. On their 1991 tour of Japan, Harrison and Clapton performed a live version of "While My Guitar Gently Weeps" with additional background vocals. An edit combining parts of the 14 December and 17 December Tokyo performances of the song is included on the album Live in Japan.
On 3 June 2002, within the Golden Jubilee of Elizabeth II concert at Buckingham Palace Garden, Paul McCartney performed the song with Clapton, as a tribute to George Harrison who had died the year before. They were introduced by George Martin. The performance appears on the DVD release Party at the Palace.
On 29 November the same year, McCartney, Starr, Dhani Harrison, Jeff Lynne, Marc Mann, and Clapton performed "While My Guitar Gently Weeps" at the Concert for George in memory of Harrison. This version featured Clapton singing the lead vocal and playing his original guitar solo while McCartney provided background vocals and piano; Mann played Clapton's original fills during the verses.